The significance, assessment, and management of nonrestorative sleep
in fibromyalgia syndrome.
CNS Spectr. 2008 Mar;13(3 Suppl 5):22-6.
Moldofsky H.
Sleep Disorders Clinic of the Centre for Sleep and Chronobiology,
Toronto, Ontario, Canada. h.moldofsky@utoronto.ca
PMID: 18323770
People with fibromyalgia syndrome (FMS) experience unrefreshing
sleep, aches, hypersensitivity, and cognitive and emotional
difficulties. Although no specific causative factor or biological
agent is known to account for all of the features of FMS and these
related diagnoses, the generalized hypersensitivity of the body is
considered to be affected by disturbances in central nervous system
(CNS) functions.
Such CNS disturbances are intrinsic to the sleeping-waking brain,
where the common symptom elements in all these illnesses are poor
quality of sleep, nonspecific pain, fatigue, and psychological
distress in the absence of known disease pathology.
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